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  • Title: Detection of autoantibodies against NMDA-type glutamate receptor in a patient with recurrent optic neuritis and transient cerebral lesions.
    Author: Ishikawa N, Tajima G, Hyodo S, Takahashi Y, Kobayashi M.
    Journal: Neuropediatrics; 2007 Oct; 38(5):257-60. PubMed ID: 18330842.
    Abstract:
    We describe the case of a Japanese girl with recurrent optic neuritis and transient cerebral lesions. Antibodies against N-methyl-d-aspartate (NMDA)-type glutamate receptors were detected in both serum and cerebrospinal fluid. Results of this case study suggest that the development of autoantibodies against NMDA-type glutamate receptors may play a role in the pathogenesis of central nervous system demyelinating diseases.
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