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  • Title: Facile synthesis of methyl alpha- and beta-D-[6-(3)H]galactofuranosides from D-galacturonic acid. Substrates for the detection of galactofuranosidases.
    Author: Bordoni A, Lima C, Mariño K, de Lederkremer RM, Marino C.
    Journal: Carbohydr Res; 2008 Jul 21; 343(10-11):1863-9. PubMed ID: 18336804.
    Abstract:
    Galactofuranose metabolism is a good target for the development of novel chemotherapeutic agents for the treatment of some microbial infections. A simple procedure for the synthesis of methyl (methyl alpha,beta-D-galactopyranosid)uronate followed by NaB(3)H(4) reduction gave a straightforward access to radiolabeled substrates for galactofuranosidases.
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