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  • Title: On stent-graft models in thoracic aortic endovascular repair: a computational investigation of the hemodynamic factors.
    Author: Fung GS, Lam SK, Cheng SW, Chow KW.
    Journal: Comput Biol Med; 2008 Apr; 38(4):484-9. PubMed ID: 18342843.
    Abstract:
    In treating thoracic aortic diseases, endovascular repair involves the placement of a self-expanding stent-graft system across the diseased thoracic aorta. Computational fluid dynamic techniques are applied to model the blood flow by numerically solving the three-dimensional continuity equation and the time-dependent Navier-Stokes equations for an incompressible fluid. From our results, high blood pressure level and high systolic slope of the pressure waveform will significantly increase the drag force on a stent-graft whereas high blood viscosity causes only a mild increase. It indicates that hemodynamic factors might have an important impact on the drag force and thus play a significant role in the risk of stent-graft failure.
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