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  • Title: Antifungal activity of Agapanthus africanus extractives.
    Author: Singh DN, Verma N, Raghuwanshi S, Shukla PK, Kulshreshtha DK.
    Journal: Fitoterapia; 2008 Jun; 79(4):298-300. PubMed ID: 18343601.
    Abstract:
    The ethanolic extract of the rhizomes of Agapanthus africanus showed antifungal activity. In bioassay guided fractionation, n-butanol fraction exhibited significant activity against human pathogens. A saponin, (25R)-spirost-7-en-2alpha,3beta,5alpha-triol-3-O-[alpha-L-rhamnopyranosyl(1-->2)-[beta-D-galactopyranosyl (1-->3)] beta-D-glucopyranoside (1), responsible for the antifungal activity and having MIC value of 15.6 microg/ml against Trychophyton mentagrophytes and Sporothrix schenekii, was isolated and identified as active constituent of the plant.
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