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Title: A comparison of the effectiveness of intravenous immunoglobulin and plasma exchange as preoperative therapy of myasthenia gravis. Author: Jensen P, Bril V. Journal: J Clin Neuromuscul Dis; 2008 Mar; 9(3):352-5. PubMed ID: 18344718. Abstract: OBJECTIVES: Immunomodulation with plasma exchange is effective in preparing patients for thymectomy. Newer forms of immunomodulation, such as intravenous immunomodulation, require evaluation in this clinical setting. METHODS: We conducted a retrospective chart review to determine if plasma exchange and intravenous immunoglobulin had comparable effectiveness in the preoperative preparation of patients with myasthenia gravis. RESULTS AND CONCLUSIONS: The results show that intravenous immunoglobulin may have comparable efficacy in the preoperative preparation of patients with myasthenia gravis and that this therapy is a reasonable alternative to plasma exchange in this clinical setting.[Abstract] [Full Text] [Related] [New Search]