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  • Title: Brianodins A-D, briarane-type diterpenoids from soft coral Pachyclavularia sp.
    Author: Ishiyama H, Okubo T, Yasuda T, Takahashi Y, Iguchi K, Kobayashi J.
    Journal: J Nat Prod; 2008 Apr; 71(4):633-6. PubMed ID: 18345642.
    Abstract:
    Four new briarane-type diterpenoids, brianodins A-D ( 1- 4), were isolated from a soft coral, Pachyclavularia sp., and the structures and relative stereochemistry of 1- 4 were elucidated on the basis of spectroscopic data. The absolute configurations of 3 and 4 were assigned by the MTPA method. Brianodin A ( 1) showed a modest cytotoxicity.
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