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  • Title: HPV-related anogenital disease and HIV infection: not always 'ordinary' condylomata acuminata.
    Author: Mudrikova T, Jaspers C, Ellerbroek P, Hoepelman A.
    Journal: Neth J Med; 2008 Mar; 66(3):98-102. PubMed ID: 18349464.
    Abstract:
    Human papillomavirus (HPV) is responsible for various diseases in the anogenital region which range from benign condylomata acuminata to anal carcinoma. Buschke-Loewenstein tumour is a clinically 'intermediate' condition which is histologically benign but due to extensive destruction of the local tissues can show malignant behaviour. Its early recognition as a different clinical entity to 'ordinary' condylomata acuminata is important for its adequate management. Immunocompromised persons, such as those with HIV infection, have a higher incidence of HPV-related anogenital disease. Different aspects of the HPV-related anogenital disease in HIV-positive individuals are discussed.
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