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  • Title: Acylated triterpenoid saponins from Schima noronhae and their cell growth inhibitory activity.
    Author: Ohtsuki T, Miyagawa T, Koyano T, Kowithayakorn T, Kawahara N, Goda Y, Ishibashi M.
    Journal: J Nat Prod; 2008 May; 71(5):918-21. PubMed ID: 18351742.
    Abstract:
    Two new acylated triterpenoid saponins were isolated from the branches of Schima noronhae by bioassay-guided purification. Their chemical structures were established on the basis of spectroscopic analysis and chemical means as 3-O-alpha-L-rhamnopyranosyl-(1-->4)-beta-D-galactopyranosyl-(1-->3)-[beta-D-glucopyranosyl-(1-->2)]-beta-D-glucuronopyranosyl 22-O-angeloyl-A1-barrigenol (1) and 3-O-alpha-L-rhamnopyranosyl-(1-->4)-beta-D-galactopyranosyl-(1-->3)-[beta-D-glucopyranosyl-(1-->2)]-beta-D-glucuronopyranosyl 22-O-angeloylerythrodiol (2). Compounds 1 and 2 showed cell growth inhibitory activity against both HeLa and DLD1 cells at a concentration of less than 10 microM.
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