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  • Title: Headache in primary Sjögren's syndrome: a prevalence study.
    Author: Gökçay F, Oder G, Celebisoy N, Gökçay A, Sirin H, Kabasakal Y.
    Journal: Acta Neurol Scand; 2008 Sep; 118(3):189-92. PubMed ID: 18355394.
    Abstract:
    OBJECTIVES: To determine the prevalence of headache in patients with primary Sjögren's syndrome (pSS) and to examine the relationship between headache types and clinical, serologic features of the disease. METHODS: The study enclosed 133 patients with the diagnoses of pSS and 97 healthy controls. A questionnaire designed to assess the presence of headache and if present to classify it according to the criteria of the International Headache Society was used. RESULTS: In 133 of the pSS patients evaluated, 104 had headache. No association was present between types of headache and the clinical and laboratory manifestations of the disease. Both migraine and tension-type headache were more common in patients with pSS when compared with healthy controls (P < 0.001). CONCLUSIONS: The high prevalence of migraine in pSS patients might be explained by a vascular headache triggered by immuno-mediated disease activity without an obvious clinic or laboratory marker.
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