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  • Title: In vitro antibiotic susceptibility of preoperative normal conjunctival bacteria.
    Author: Ta CN, He L, Mino de Kaspar H.
    Journal: Eye (Lond); 2009 Mar; 23(3):559-60. PubMed ID: 18356928.
    Abstract:
    PURPOSE: To determine the antibiotic susceptibility of preoperative conjunctival bacterial flora. METHODS: Antibiotic susceptibility of conjunctival bacterial strains isolated from 142 patients undergoing intraocular surgery was determined using the Kirby-Bauer disc diffusion technique. chi(2) statistical analysis was performed. RESULTS: Among the 116 bacteria isolated, 95 (82%) were coagulase-negative staphylococci (CNS). Most (>75%) of them were susceptible to vancomycin, minocycline, aminoglycosides, gatifloxacin, levofloxacin, and moxifloxacin. Approximately one-half of CNS was resistant to erythromycin and azithromycin. Over 90% of streptococci were susceptible to levofloxacin, moxifloxacin, and gatifloxacin. RESULTS: Fluoroquinolones, specifically gatifloxacin, levofloxacin, and moxifloxacin continue to provide broad-spectrum coverage against common conjunctival bacterial flora.
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