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  • Title: Inverted fixation-off sensitivity in atypical benign partial epilepsy.
    Author: Nicolai J, Vles JS, van Tellingen V, van Kranen-Mastenbroek VH.
    Journal: Pediatr Neurol; 2008 Apr; 38(4):279-83. PubMed ID: 18358409.
    Abstract:
    Fixation-off sensitivity is an electroencephalographic phenomenon characterized by spike-and-wave discharges that only occur when central vision and fixation are eliminated. It is especially seen in children with Panayiotopoulos-type, early-onset, benign childhood occipital epilepsy or Gastaut type, late-onset, childhood occipital epilepsy. It can also be seen in eyelid myoclonia with absences, in other idiopathic generalized epilepsies, and in asymptomatic children without epilepsy. We describe a boy with atypical, benign partial epilepsy of childhood who exhibited the reverse: epileptiform activity that was suppressed by the absence of central vision or fixation, and activated by central vision or fixation.
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