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  • Title: Uterine leiomyoma with associated pseudo-Meigs syndrome mimicking ovarian carcinoma.
    Author: Landrum LM, Rutledge TL, Osunkoya AO, Mannel R.
    Journal: J Okla State Med Assoc; 2008 Feb; 101(2):38-9. PubMed ID: 18361033.
    Abstract:
    BACKGROUND: Uterine leiomyoma are commonly diagnosed in women of reproductive age. However, these benign tumors may present with clinical signs and symptoms that are consistent with ovarian carcinoma. CASE: A 47-year-old gravida 0 presented with a large pelvic mass, ascites, bilateral pleural effusions, and an elevated CA 125 worrisome for ovarian carcinoma. Exploratory laparotomy revealed a 20,120 g pelvic mass, with 2 L ascites, and pelvic and periaortic lymphadenopathy. Final pathology was consistent with a benign giant leiomyoma. Postoperative course was complicated by reaccumulation of pleural effusion requiring therapeutic thoracentesis and diuretics. Patient had return to full activity with 50 pound weight loss at 8 weeks after surgery. CONCLUSION: Elevated CA 125 levels and ascites are often associated with ovarian carcinoma, but it is also important to keep benign processes in the differential diagnosis when considering malignancy.
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