These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Novel technique of corneal biopsy by using a femtosecond laser in infectious ulcers.
    Author: Kim JH, Yum JH, Lee D, Oh SH.
    Journal: Cornea; 2008 Apr; 27(3):363-5. PubMed ID: 18362669.
    Abstract:
    PURPOSE: To describe femtosecond laser-assisted corneal biopsy and its use in assessing the causative organisms in 2 cases of infectious corneal ulcers. METHODS: A 27-year-old man and a 65-year-old woman, both of whom showed uncertain symptoms, repeated negative test results for infectious organisms, and after no improvement despite empirical therapy, underwent diagnostic corneal biopsy by using a femtosecond laser. A corneal flap depth of 200 microm and a diameter of 3 mm were obtained from each patient. RESULTS: The biopsy specimen from the male patient showed pseudohyphae, which led to a diagnosis of candidal keratitis. The biopsy specimen from the female patient showed positive Gram stain and no evidence of fungal ulcers and yielded a culture of Streptococcus viridans. No complications occurred during either procedure. CONCLUSIONS: Femtosecond laser-assisted corneal biopsy enabled identification of the infectious pathogen in both patients. This technique is easy, safe, and rapid, and it yields a biopsy specimen with a uniform depth and precise size. Femtosecond laser-assisted corneal biopsy can be used as an accurate diagnostic method in uncertain cases of corneal ulcers.
    [Abstract] [Full Text] [Related] [New Search]