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  • Title: [Histopathological techniques for diagnosing cryptococcosis due to capsule-deficient Cryptococcus: case report].
    Author: Gazzoni AF, Pegas KL, Severo LC.
    Journal: Rev Soc Bras Med Trop; 2008; 41(1):76-8. PubMed ID: 18368276.
    Abstract:
    A case of cryptococcosis due to capsule-deficient Cryptococcus is presented, in which culturing of the clinical specimen and tests for capsular antigen in cerebrospinal fluid and serum were negative. The histopathological techniques evaluated were hematoxylin-eosin, Grocott methenamine silver, Mayers mucicarmine and Fontana-Masson. The diagnosis of cryptococcosis due to capsule-deficient Cryptococcus was confirmed by means of the Fontana-Masson technique and by direct immunofluorescence. The potential of the histochemical techniques is discussed.
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