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  • Title: Efficacy, effectiveness and cost-effectiveness of endoscopic screening methods.
    Author: Brenner H.
    Journal: Z Gastroenterol; 2008 Apr; 46 Suppl 1():S20-2. PubMed ID: 18368634.
    Abstract:
    Epidemiological evidence suggests that incidence of colorectal cancer can be reduced by 60-90% among participants of preventive colonoscopy with removal of precancerous lesions. Even with sigmoidoscopy, the majority of cancers can be prevented. Cost-effectiveness analyses suggest screening schemes based on colonoscopy every 10 years or on sigmoidoscopy every 5 years to be highly cost effective compared to other preventive measures. Even higher cost-effectiveness is to be expected if screening intervals can be extended to 20 or more years, as suggested by recent epidemiological evidence.
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