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  • Title: [Effect of corticotropin on functional and metabolic processes in muscles].
    Author: Korkach VI.
    Journal: Fiziol Zh SSSR Im I M Sechenova; 1977 Jun; 63(6):852-7. PubMed ID: 18370.
    Abstract:
    Changes of excitability, contractility, temperature, activity of oxydation-reduction enzymes, pyridine nucleotides, and of free fatty acids were studied in m. m. gastrocnemii of rabbits and rats during activity, after administration of 1 unit per 100 g of corticotropin (ACTH). Within 30 min after administration, the ACTH did not alter the excitability of a neural-muscular system but increased its efficiency by means of stimulation of the free fatty acids usage. Besides, the ACTH elicits no regular changes of the oxydation--reduction enzymes activity during a short-lasting muscular activity. Its regulating effect on the metabolic processes in muscles is realised at the level of anaerobic processes.
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