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  • Title: Bioactive porous titanium: an alternative to surgical implants.
    Author: de Medeiros WS, de Oliveira MV, Pereira LC, de Andrade MC.
    Journal: Artif Organs; 2008 Apr; 32(4):277-82. PubMed ID: 18370941.
    Abstract:
    Porous titanium implants have been used to improve implant-bone attachment by the ingrowth of bone tissue within the porous structure. Despite the efficient bone adhesion of porous titanium implants, chemical bonds are required at bone-implant interface. These implants can become bioactive by a biomimetic precipitation process. The aim of this work was to enhance the bioactivity of pure porous titanium implants by biomimetic process. The samples immersed in a simulated body fluid promoted the nucleation and growth of calcium phosphate (Ca-P) crystals, such as hydroxyapatite (Hap), on the material surface. Scanning electron microscopy, energy dispersive spectroscopy, and Fourier transform infrared spectroscopy analyses revealed that a Ca-P deposition occurred without the need of pretreatments to improve the surface bioactivity. This present study indicates the potential for growing a bone-like Hap layer on porous titanium implants by biomimetic processes.
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