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  • Title: Gadofullerene MRI contrast agents.
    Author: Bolskar RD.
    Journal: Nanomedicine (Lond); 2008 Apr; 3(2):201-13. PubMed ID: 18373426.
    Abstract:
    A promising new class of MRI contrast-enhancing agents with high relaxivities is based on gadolinium-containing metallofullerenes, which are also termed gadofullerenes. Detailed study of the water-proton relaxivity properties and intermolecular nanoclustering behavior of gadofullerene derivatives has revealed valuable information about their relaxivity mechanisms and given a deeper understanding of this new class of paramagnetic contrast agent. Here, the latest findings on water-solubilized gadofullerene materials and how these findings relate to their future applications in MRI are reviewed and discussed.
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