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  • Title: Levator superioris muscle function in involutional blepharoptosis.
    Author: Pereira LS, Hwang TN, Kersten RC, Ray K, McCulley TJ.
    Journal: Am J Ophthalmol; 2008 Jun; 145(6):1095-1098. PubMed ID: 18374300.
    Abstract:
    PURPOSE: To assess the role of muscular degeneration, we evaluated the correlation between ptosis severity and levator muscle function. DESIGN: Retrospective cohort study. METHODS: The medical records of 136 patients (53 men and 83 women; mean age, 67 years) with acquired blepharoptosis were reviewed for levator function (LF), margin reflex distance (MRD), age, and gender. Multivariate linear regression was performed for statistical analysis. RESULTS: A significant correlation (P < .001) was seen between MRD (mean, 1.0 + 1.0 mm; range, -3.0 to 3.0 mm) and LF (mean, 15.0 + 1.0 mm; range, 11.0 to 20.0 mm). On average, a 0.5-mm reduction in LF was observed for each 1.0-mm decrease in MRD. This was independent to other variables assessed. CONCLUSIONS: In patients with involutional blepharoptosis, a directly proportional decrease in levator function and eyelid height was observed. This may implicate an abnormality of the levator muscle itself as a contributing factor in the development of involutional blepharoptosis.
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