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Title: Translational research in breast cancer. Author: Chu QD, Holm N, Byrnes K, Li BD. Journal: Surg Oncol Clin N Am; 2008 Apr; 17(2):421-38, x. PubMed ID: 18375360. Abstract: The discovery of 25,000 human genes from the Human Genome Project has had a dramatic impact on the translational landscape of human diseases. Nowhere is the impact more apparent than in the field of cancer, specifically breast cancer. Understanding of the malignant process at a molecular level, coupled with the discovery of novel molecular techniques, has shifted the paradigm of treating breast cancer from a clinical, population-based risk assessment model to one based on molecular classification of disease.[Abstract] [Full Text] [Related] [New Search]