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  • Title: Mechanisms of macrolide resistance among Streptococcus pneumoniae isolates from Russia.
    Author: Reinert RR, Filimonova OY, Al-Lahham A, Grudinina SA, Ilina EN, Weigel LM, Sidorenko SV.
    Journal: Antimicrob Agents Chemother; 2008 Jun; 52(6):2260-2. PubMed ID: 18378707.
    Abstract:
    Among 76 macrolide-nonsusceptible Streptococcus pneumoniae isolates collected between 2003 and 2005 from Central Russia, the resistance mechanisms detected in the isolates included erm(B) alone (50%), mef alone [mef(E), mef(I), or a different mef subclass; 19.7%], or both erm(B) and mef(E) (30.3%). Isolates with dual resistance genes [erm(B) and mef(E)] belonged to clonal complex CC81 or CC271.
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