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  • Title: Difficulties in diagnosis and management of ectopic Cushing syndrome.
    Author: Cho S, Ra YJ, Lee CT, Chung JH, Sung SW, Jheon S.
    Journal: J Thorac Oncol; 2008 Apr; 3(4):444-6. PubMed ID: 18379368.
    Abstract:
    A 18-year-old man presented to a local hospital with muscle weakness, facial edema, and a 6 kg weight gain over 2 months. After a complete work-up, he was diagnosed with pituitary Cushing syndrome and treated with a bilateral adrenalectomy for Cushing syndrome and pituitary radiotherapy for Nelson syndrome. Twenty-five years later, his ectopic source of adrenocorticotropic hormone was revealed as a pulmonary neuroendocrine tumor, and a pulmonary resection was performed. Subsequently, a biochemical and clinical remission including hyperpigmentation was achieved.
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