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  • Title: Good's syndrome in a patient with cytomegalovirus retinitis.
    Author: Yong DS, Tsang MK, Chan EY, Tse DM.
    Journal: Hong Kong Med J; 2008 Apr; 14(2):142-4. PubMed ID: 18382022.
    Abstract:
    Thymoma-related adult-onset immunodeficiency or Good's syndrome is an uncommon condition. This case, of a 50-year-old woman who was human immunodeficiency virus-negative and developed herpes zoster and severe cytomegalovirus retinitis 6 months after removal of a thymoma, is the first to be reported in Hong Kong. Immunological investigations revealed no B cells, hypogammaglobulinaemia, a low CD4 count, and a low CD4/CD8 ratio. We recommend that immunological investigations, including T-cell subsets, B cells, and quantitative immunoglobulins, should be part of the routine diagnostic evaluation of patients with thymoma and infections.
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