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  • Title: [Multicentric clinical trial of a combination of 35 micrograms of ethinylestradiol and 2 mg of cyproterone acetate].
    Author: Audebert A, Emperaire JC, Gauthier A, Hallonet P, Hedon B, Lopes P, Quereux C, Roulier R.
    Journal: Rev Fr Gynecol Obstet; 1991 Nov; 86(11):697-9. PubMed ID: 1838208.
    Abstract:
    The authors report the results of an open multicentric study of 136 women treated by a combination of 35 micrograms ethinylestradiol and 2 mg cyproterone acetate for cutaneous manifestation of hyperandrogenism. No pregnancy occurred during the treatment of 12 months. Comparison between the last treated and non treated cycle showed a significant difference (p less than 0.001) in the severity of acne lesions regardless of their sites. General and gynaecological tolerance were excellent.
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