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  • Title: Interaction between methotrexate and omeprazole in an adolescent with leukemia: a case report.
    Author: Bauters TG, Verlooy J, Robays H, Laureys G.
    Journal: Pharm World Sci; 2008 Aug; 30(4):316-8. PubMed ID: 18386155.
    Abstract:
    We present a case of severe mucositis due to a drug-drug interaction between methotrexate (MTX) and omeprazole in an adolescent with Acute Lymphatic Leukemia (ALL). In view of the prevalence of MTX in many cytotoxic protocols, and the frequent use of omeprazole in the (ambulatory) oncology setting, we believe that this case-report is worth mentioning.
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