These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Asymmetric catalysis via dynamic substrate/ligand/rare earth metal conglomerate.
    Author: Nojiri A, Kumagai N, Shibasaki M.
    Journal: J Am Chem Soc; 2008 Apr 30; 130(17):5630-1. PubMed ID: 18393416.
    Abstract:
    A highly enantio- and diastereoselective catalytic asymmetric Mannich-type reaction of alpha-cyanoketones and N-Boc imines promoted by an amide ligand/Sc(OiPr)3 catalyst is described. The similar reaction outcome is obtained with/without precomplexation of catalyst, suggesting that reaction components in a non-ordered conglomerate mixture orchestrate to form an ordered transition state during the reaction. Spectroscopic data and Eyring plot are consistent with this assumption.
    [Abstract] [Full Text] [Related] [New Search]