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  • Title: Semisynthesis of dimeric proteins by expressed protein ligation.
    Author: Ziaco B, Pensato S, D'Andrea LD, Benedetti E, Romanelli A.
    Journal: Org Lett; 2008 May 15; 10(10):1955-8. PubMed ID: 18410123.
    Abstract:
    A one-pot synthesis of homodimeric proteins is described. The synthetic strategy is based on a double expressed protein ligation reaction between thioester peptides and a new bis-cysteinyl linker. The protocol was also applied to the synthesis of heterodimers.
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