These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
Pubmed for Handhelds
PUBMED FOR HANDHELDS
Search MEDLINE/PubMed
Title: Neurochemical basis of conditioned partner preference in the female rat: I. Disruption by naloxone. Author: Coria-Avila GA, Solomon CE, Vargas EB, Lemme I, Ryan R, Ménard S, Gavrila AM, Pfaus JG. Journal: Behav Neurosci; 2008 Apr; 122(2):385-95. PubMed ID: 18410177. Abstract: The effects of the opioid antagonist naloxone were examined on the development of conditioned partner preference induced by paced copulation in female rats. In Experiment 1, ovariectomized, hormone-primed rats were conditioned to associate scented and unscented male rats with paced and nonpaced copulation, respectively. Female rats in Experiment 2 associated albino or pigmented male rats with paced or nonpaced copulation. Naloxone or saline was administered before each conditioning trial. During a final drug-free preference test, female rats could choose to copulate with either a pacing related or unrelated male. Saline-trained female rats in the paired group copulated preferentially with the pacing-related male rat, whereas naloxone-trained female rats did not show a preference. The authors concluded that opioids mediated the conditioned partner preference induced by paced copulation.[Abstract] [Full Text] [Related] [New Search]