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  • Title: The effect of lithium on haematopoiesis of patients with acute myeloid leukaemia.
    Author: Korycka A, Robak T.
    Journal: Arch Immunol Ther Exp (Warsz); 1991; 39(5-6):501-9. PubMed ID: 1841548.
    Abstract:
    In 40 patients receiving induction therapy for acute myeloid leukaemia the influence of lithium carbonate on the regeneration of haematopoiesis was investigated. It was observed that lithium treatment decreases chemotherapy-induced suppression of granulo- and megacariopoiesis. The frequency of remissions and the survival time were significantly higher for the patients receiving lithium if compared with the control group. The number of CFU-GM colonies in vitro after 14-th days of incubation was also statistically higher in the lithium treated patients.
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