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Title: Scalable preparation of both enantiomers of 2-(1-hydroxy-2-oxocyclohexyl)acetic acid. Author: Vamos M, Kobayashi Y. Journal: J Org Chem; 2008 May 16; 73(10):3938-41. PubMed ID: 18416575. Abstract: The efficient, scalable preparation of both enantiomers of 2-(1-hydroxy-2-oxocyclohexyl)acetic acid in enantiomerically pure form is reported using environmentally benign conditions in 30% overall yield (6 steps) for the (S)-isomer, in 27% (7 steps) for the (R)-isomer, from cyclohexanone.[Abstract] [Full Text] [Related] [New Search]