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  • Title: Fetal loss after amniocentesis in a series of 5,780 procedures.
    Author: Gaudry P, Grangé G, Lebbar A, Choiset A, Girard S, Goffinet F, Lewin F.
    Journal: Fetal Diagn Ther; 2008; 23(3):217-21. PubMed ID: 18417981.
    Abstract:
    OBJECTIVES: Counseling on prenatal diagnosis requires accurate knowledge of the associated risks, including fetal loss. The objective of our study was to assess this risk of amniocentesis in a single center with several operators. METHODS: This retrospective analysis concerns only women with singleton pregnancies who underwent amniocentesis between 14(+0) and 23(+6) weeks' gestation. RESULTS: During this 4.5-year period, 5,780 amniocenteses were performed, of which we analyzed 5,319. The rate of fetal loss was 70 in 4,858 tests (1.4%), with a lost-to-follow-up rate of 3.8%. CONCLUSION: Our results for fetal loss are comparable to those in the largest series with fewer operators already published.
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