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  • Title: [The transcatheter ablation of arrhythmias].
    Author: Critelli G, Yang Y, Urbani P, Greco C, Ambrosini M, Sinatra R, Campa PP, Marino B.
    Journal: Cardiologia; 1991 Dec; 36(12 Suppl 1):469-84. PubMed ID: 1841803.
    Abstract:
    The introduction of transcatheter ablation techniques has opened a new era of the management of tachyarrhythmias. The rationale of these therapeutic procedures lies in the induction of an irreversible and limited damage to cardiac tissue involved in arrhythmias. In its original form, the technique involves the delivery of high energy DC discharges (fulguration) to the target area through a temporary catheter electrode. A primary drawback of fulguration, when used for ablation of AV node-His bundle, is the induction of a pacemaker-dependent state; the barotraumatic effect that results from high energy impulses constitutes the major limitation in the case of ablation of accessory pathways or arrhythmogenic areas. Recently, the efficiency of the procedure has been substantially improved by the use of low-power, high-frequency alternating current (radiofrequency), that allows to deliver graded amounts of disrupting energy to selected areas while avoiding undesirable biophysical effects to the surrounding tissue. Remarkable results, with a success rate close to 100%, are reported with radiofrequency ablation of AV node reentry tachycardia, as well as reciprocating tachycardia associated with the preexcitation syndrome, so that this technique can be considered the procedure of choice for both categories of patients. Catheter modification of AV conduction provides a therapeutic tool for treating atrial tachyarrhythmias with rapid ventricular responses. In such cases, however, the risk of AV block with the need for pacemaker implantation must be taken into account. Results of catheter ablation of ventricular tachycardia have been inconstant and generally disappointing, except for ventricular tachycardias due to reentry in the His-Purkinje system, for which a high success rate is reported. Experience with radiofrequency ablation in ventricular tachycardia is very limited, but localization of a critical segment of reentry could improve the efficiency of this technique.
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