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  • Title: Anti-trichomonad IgA antibodies in trichomoniasis before and after treatment.
    Author: Sharma P, Malla N, Gupta I, Ganguly NK, Mahajan RC.
    Journal: Folia Microbiol (Praha); 1991; 36(3):302-4. PubMed ID: 1841864.
    Abstract:
    Anti-trichomonad IgA antibodies were estimated by enzyme-linked immunosorbent assay (ELISA) in serum and vaginal secretions of 25 symptomatic and 25 asymptomatic Trichomonas vaginalis positive patients before and after treatment and in 25 age-matched controls. Significantly higher levels of antitrichomonad IgA antibodies were found in T. vaginalis positive patients when compared to control subjects, especially in vaginal secretions. In addition, a significant decrease in these antibodies was observed after treatment, which was more pronounced in vaginal secretions. It seems that anti-trichomonad IgA antibodies in serum and more so in vaginal secretions are directly related to and specific to the presence of T. vaginalis in the urogenital tract.
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