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  • Title: Synthesis and characterization of flavin modified oligodeoxyribonucleotide.
    Author: Akiyama T, Yoneda F, Tanaka K, Kuwabara J, Sugiura Y.
    Journal: Nucleic Acids Symp Ser; 1991; (25):69-70. PubMed ID: 1842100.
    Abstract:
    Oligonucleotides covalently linked to isoalloxazines via polymethylene linker were synthesized and characterized. The thymidine decamer having a primary aminoalkyl group at the 5'-end of internucleotide linkage was coupled with the activated ester of isoalloxazine in liquid-phase. The interaction of the flavin modified thymidine decamers with polydA was investigated by using spectrophotometric method.
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