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  • Title: [Study on the formulation and process of Da Chuan Xiong Fang pellet by extrusion-spheronization].
    Author: Hong YL, Feng Y, Xu DS, Jiang LH, Yang Y.
    Journal: Zhong Yao Cai; 2007 Dec; 30(12):1596-600. PubMed ID: 18422197.
    Abstract:
    OBJECTIVE: To study on the formulation and process of Da Chuan Xiong Fang pellet by extrusion-spheronization. METHODS: Based on the physical characters of active parts, the fast-release pellets of Chuan Xiong and Tian Ma were prepared separately by extrusion-spheronization. The formulation and process were studied by direct comparison. Then their characters were evaluated. RESULTS: The active components could release more than 90% in 30 minutes and the pellets presented perfect sphericity and narrow diameter distribution. CONCLUSION: Pellets of TCM can be prepared by homemade extrusion-spheronization machine and the fast-release pellets show perfect sphericity and narrow diameter distribution.
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