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  • Title: Integrating whole-genome expression results into metabolic networks with Pathway Processor.
    Author: Cavalieri D, Grosu P.
    Journal: Curr Protoc Bioinformatics; 2004 May; Chapter 7():Unit 7.6. PubMed ID: 18428732.
    Abstract:
    Genes never act alone in a biological system, but participate in a cascade of networks. As a result, analyzing microarray data from a pathway perspective leads to a new level of understanding the system. The authors' group has recently developed Pathway Processor (http://cgr.harvard.edu/cavalieri/pp.html), an automatic statistical method to determine which pathways are most affected by transcriptional changes and to map expression data from multiple whole-genome expression experiments on metabolic pathways. This unit presents applications of the Pathway Processor software.
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