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  • Title: Recent advances in RNA structure determination by NMR.
    Author: Hennig M, Williamson JR, Brodsky AS, Battiste JL.
    Journal: Curr Protoc Nucleic Acid Chem; 2001 May; Chapter 7():Unit 7.7. PubMed ID: 18428875.
    Abstract:
    Despite recent advances in the solution of NMR structures of RNA and RNA-ligand complexes, the rate limiting step remains the gathering of a large number of NOE and torsion restraints. Additional sources of information for structure determination of larger RNA molecules have recently become available, and it is possible to supplement NOE and J-coupling data with the measurement of dipolar couplings and cross-correlated relaxation rates in high-resolution NMR spectroscopy.
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