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  • Title: Facile fabrication of multi-colors high fluorescent/superparamagnetic nanoparticles.
    Author: Zhang B, Cheng J, Gong X, Dong X, Liu X, Ma G, Chang J.
    Journal: J Colloid Interface Sci; 2008 Jun 15; 322(2):485-90. PubMed ID: 18430431.
    Abstract:
    We developed a novel method to prepare multi-colors high fluorescent/superparamagnetic nanoparticles (FMNPs) employing hydrophobic multi-color quantum dots (QDs) and hydrophobic Fe(3)O(4) (MNPs) via ultrasonic emulsification method. This structural procedure was simple, one-off, and timesaving. Different-sizes FMNPs with encoding single/multi-color QDs and MNPs were achieved. Analysis with transmission electron microscopy (TEM) and particle size analyzer demonstrated that the as-prepared samples were spherical, uniform in size distribution; Ultraviolet-visible (UV-vis) absorption spectroscopy and photoluminescence (PL) measurement showed the FMNPs had good optical properties, lacking of fluorescence resonance energy transfer (FRET) inside FMNPs; vibrating sample magnetometer (VSM) indicated that FMNPs were superparamagnetic. These results indicate that the as-prepared FMNPs have potential of serving as a hybrid of QDs and MNPs in bioanalysis communities.
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