These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: UV-enhanced bioactivity and cell response of micro-arc oxidized titania coatings.
    Author: Han Y, Chen D, Sun J, Zhang Y, Xu K.
    Journal: Acta Biomater; 2008 Sep; 4(5):1518-29. PubMed ID: 18430620.
    Abstract:
    Using ultraviolet (UV) irradiation of micro-arc oxidized (MAO) titania coating in distilled water for 0.5 and 2h, we have achieved an enhanced bioactivity and cell response to titania surface. The MAO coating appears porous and predominantly consists of nanocrystallized anatase TiO(2). Compared with the MAO coating, the UV-irradiated coatings do not exhibit any obvious change in surface roughness, morphology, grain size and phase component; however, they have more abundant basic Ti-OH groups and become more hydrophilic because the water contact angle decreases significantly from 17.9+/-0.8 degrees to 0 degrees . In simulated body fluid (SBF), bonelike apatite-forming ability is significantly stronger on the UV-irradiated coatings than the MAO coating. SaOS-2 human osteoblast-like cell attachment, proliferation and alkaline phosphatase of the cell are greater on the UV-irradiated coatings relative to the MAO coating. UV irradiation of titania results in the conversion of Ti(4+) to Ti(3+) and the generation of oxygen vacancies, which could react with the absorbed water to form basic Ti-OH groups. The enhanced bioactivity and cell response of the UV-irradiated coatings are proven to result from abundant Ti-OH groups on the coating surfaces. After storing the UV-irradiated coatings in the dark for two weeks, the basic Ti-OH groups on the coatings slightly decrease in amount and can induce apatite formation after a short period of SBF immersion, and show relative long-term stability.
    [Abstract] [Full Text] [Related] [New Search]