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  • Title: [The hemostatic state of patients with breast and lung cancer undergoing hypoxic radiotherapy].
    Author: Chekalina SI, Medvedev VN, Firsova PP.
    Journal: Vopr Onkol; 1991; 37(6):723-7. PubMed ID: 1843152.
    Abstract:
    Parameters of functional status of the hemostatic system were studied in 76 breast and lung cancer patients in the course of radiotherapy using TTC-10 hypoxic gas mixture (oxygen--10% and nitrogen--90%) as radioprotector. The thrombophilic status of the blood in breast and lung cancer patients established prior to treatment was accounted for by increased functional activity of platelets, increased capillary blood coagulability, formation of dense clot and inhibition of fibrinolysis. In the course of hypoxyradiotherapy, blood thrombogeneity becomes lower due to a decrease in platelet adhesion.
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