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  • Title: Orbital tumour as initial manifestation of acute myeloid leukemia: granulocytic sarcoma: case report.
    Author: Maka E, Lukáts O, Tóth J, Fekete S.
    Journal: Pathol Oncol Res; 2008 Jun; 14(2):209-11. PubMed ID: 18431695.
    Abstract:
    We report orbital involvement as an initial manifestation of acute myeloid leukemia in a 57-year-old woman. The patient presented with painful proptosis and limited ocular motility. Orbital computed tomography revealed bilateral homogeneous masses. Orbital biopsy was performed on the right side; and histopathology disclosed a myelocytic tumour. Despite treatment using irradiation and chemotherapy, the patient died eleven months after presentation. There appear to be only a few previous reports of acute myeloid leukemia cases presenting with orbital involvement, and most cases occurred in children. This very rare condition has a poor survival prognosis, even with radiation treatment and chemotherapy.
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