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  • Title: [Mesenteric and portal vein thrombosis following splenectomy in hematologic diseases. Apropos of 3 cases].
    Author: Boissel P, Bresler L, Trackoen G, Poussot D, Grosdidier J.
    Journal: Chirurgie; 1991; 117(8):591-5; discussion 595-6. PubMed ID: 1843213.
    Abstract:
    Mesenterico-portal venous thrombosis following hematological splenectomy is infrequent. We report about three cases successfully treated with heparin. A review of the literature allows identifying three factors acting in the etiopathogenesis of such thrombosis: alteration of blood composition, blood stasis and injuries to the vascular walls. The diagnosis is confirmed by ultrasonography and abdominal CT, and echo-Doppler will play a more important role in the future. The treatment of mesenterico-portal thrombosis is mainly medical, with surgery being indicated only in case of intestinal necrosis. An anticoagulant or platelet-suppressive treatment and the ligation of the splenic vein as close as possible to its junction with the mesenteric vein may be proposed as preventive measures.
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