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  • Title: Molecular phylogenetic analysis of Candida tropicalis isolates by multi-locus sequence typing.
    Author: Jacobsen MD, Davidson AD, Li SY, Shaw DJ, Gow NA, Odds FC.
    Journal: Fungal Genet Biol; 2008 Jun; 45(6):1040-2. PubMed ID: 18440253.
    Abstract:
    Multi-locus sequencing data for 242 different isolates of Candida tropicalis generated a dendrogram showing 235 strains assigned to a single large recently evolved group which contained several small clonal clusters. Haplotype analysis of a representative strain subset revealed a high level of recombination events in an otherwise clonal population. Pairs of isolates from single sources showed non-identity attributable to loss of heterozygosity in some genes in a manner similar to that established for C. albicans.
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