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  • Title: Antiproliferative oleanane saponins from Meryta denhamii.
    Author: Cioffi G, Dal Piaz F, Vassallo A, Venturella F, De Caprariis P, De Simone F, De Tommasi N.
    Journal: J Nat Prod; 2008 Jun; 71(6):1000-4. PubMed ID: 18442289.
    Abstract:
    Eight new oleanane saponins (1- 8) together with four know saponins (9-12) were isolated from the aerial parts of Meryta denhamii. Their structures were elucidated by 1D and 2D NMR experiments including 1D TOCSY, DQF-COSY, ROESY, HSQC, and HMBC spectroscopy, as well as ESIMS analysis. The antiproliferative activity of all compounds was evaluated using three murine and human cancer cell lines: J774.A1, HEK-293, and WEHI-164.
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