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  • Title: Four-fraction radiation therapy for macroscopic soft tissue sarcomas in 16 dogs.
    Author: Lawrence J, Forrest L, Adams W, Vail D, Thamm D.
    Journal: J Am Anim Hosp Assoc; 2008; 44(3):100-8. PubMed ID: 18451067.
    Abstract:
    A retrospective study of 16 dogs with macroscopic soft tissue sarcomas was performed to evaluate response to a four-fraction radiotherapy protocol (prescribed dose of 32 Gy). Radiation was well tolerated with minimal side effects. The overall response rate was 50%, with seven partial responses and one complete response. The median time to progression was 155 days, and the median survival time was 309 days. Coarsely fractionated radiation therapy may be a reasonable palliative option for dogs with unresectable soft tissue sarcomas, although the response is relatively short-lived.
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