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  • Title: [Congenital bilateral abducens paralysis and facial diplegia. The Moebius syndrome].
    Author: Cernea P, Grapă C.
    Journal: Oftalmologia; 1991; 35(3-4):79-84. PubMed ID: 1845449.
    Abstract:
    The patient, 9 years old, presents bilateral congenital paralysis of the facial, disability of the ocular globes abduction, facial cutanate atrophy and partial paralysis of hypoglos, syndrome manifestations that are framed in the disease described by Moebius. The patient also presents epicanthus, hiperthlorysm, atresia of the tear points. The disease is caused by some teratogenic factors which act between the fourth and the seventh week of the intrauterine life with the atresia of the sixth and seventh nucleus and partially of the ninth nucleus as well as of the supranuclear way from the proximity of these nucleus. The variety of the clinical manifestations can be explained through the affectation of the different nervous structures during the embryogenesis, but the congenital paralysis of the abduction and the facial diplegia are the most important manifestations of the syndrome.
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