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  • Title: Disseminated blue naevus and malignant blue naevus associated with excessive aromatase syndrome.
    Author: Lobo AZ, Martin RM, Belda W, Michi MM, Arnone M, Festa-Neo C, Sotto MN, Vilela MA, Sanches JA.
    Journal: Clin Exp Dermatol; 2008 Aug; 33(5):591-4. PubMed ID: 18462445.
    Abstract:
    We report a case of a 17-year-old boy who had a giant congenital blue naevus with multiple satellite pigmented lesions. Later the patient developed melanoma arising in the pre-existing lesion. He also had gynaecomastia and was diagnosed as having aromatase excess syndrome. To our knowledge, the association of these two rare conditions has not been previously reported. Further studies should be performed to investigate this unusual combination, which may have a genetic, endocrine or local cutaneous link leading to its occurrence.
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