These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Getting to guanine: mechanism and dynamics of charge separation and charge recombination in DNA revisited.
    Author: Lewis FD, Zhu H, Daublain P, Sigmund K, Fiebig T, Raytchev M, Wang Q, Shafirovich V.
    Journal: Photochem Photobiol Sci; 2008 May; 7(5):534-9. PubMed ID: 18465008.
    Abstract:
    The mechanism and dynamics of charge separation and charge recombination in synthetic DNA hairpins possessing a stilbenedicarboxamide linker and a single guanine-cytosine base pair have been reinvestigated. The combination of femtosecond broad-band pump probe spectroscopy, nanosecond transient absorption experiments, and picosecond fluorescence decay measurements permits analysis of the formation and decay of the stilbene anion radical. Reversible hole injection resulting in the formation of the stilbene-adenine contact radical ion pair is found to occur on the picosecond time scale. The mechanism for charge separation across two or more base pairs is revised from single step superexchange to a multi-step process: hole injection followed by hole transport and hole trapping. The mechanism of charge recombination remains assigned to a superexchange process.
    [Abstract] [Full Text] [Related] [New Search]