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  • Title: Human interferon and cell growth inhibition. I. Inhibitory effect of human interferon on the growth rate of cultured human cells.
    Author: Dahl H, Degré M.
    Journal: Acta Pathol Microbiol Scand B; 1976 Oct; 84B(5):285-92. PubMed ID: 184682.
    Abstract:
    Human interferon inhibited the growth rate of cultured human cells. These included diploid fibroblast cells from embryonal lung and skin, established lines of HeLa and U-amnion cells, all grown in monolayer; and the established lymphoblastoid line P3HR1 grown in suspension. Cells growing fast were inhibited to a higher degree than those growing slowly. The inhibitory effect was dose dependent but the dose-dependency was different in various cell types. The inhibitory effect of leukocyte interferon and fibroblast interferon was quantitatively comparable.
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