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  • Title: Photo-pH dually modulated fluorescence switch based on DNA spatial nanodevice.
    Author: Liu H, Zhou Y, Yang Y, Wang W, Qu L, Chen C, Liu D, Zhang D, Zhu D.
    Journal: J Phys Chem B; 2008 Jun 05; 112(22):6893-6. PubMed ID: 18476740.
    Abstract:
    In this paper, we describe our strategy on the design, construction, and characterization of a novel molecular device. By integrating a photoregulated fluorescent switch and a DNA-based nanomachine, the distance-dependent FRET process between fluorescein and photochromic moieties can be further modulated by the spatial output of a unique proton-driven DNA manomachine. This device could be reversibly switched in a reliable manner, and the fluorescence variation behavior, exhibited by this dually modulated fluorescence switch, can also mimic the function of a Boolean logic operation.
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